Niraparib Capsules 100mg

Description

Niraparib 100mg is a prescription medicine used for the:maintenance treatment of adults with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. Niraparib is used after the cancer has responded (complete or partial response) to treatment with platinum-based chemotherapy.maintenance treatment of adults with ovarian cancer, fallopian tube cancer, or primary peritoneal cancer that comes back. Niraparib is used after the cancer has responded (complete or partial response) to treatment with platinum-based chemotherapy.treatment of adults with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer who have been treated with 3 or more prior types of chemotherapy and who have tumors with: a certain BRCA gene mutation, orgene mutation problems and who have progressed more than 6 months after their last treatment with platinum-based chemotherapy.Your healthcare provider will perform a test to make sure that Niraparib is right for you.It is not known if Niraparib is safe and effective in children.Important Safety InformationNiraparib may cause serious side effects, including:Bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of blood cancer called Acute Myeloid Leukemia (AML). Some people who have ovarian cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during treatment with Niraparib . MDS or AML may lead to death.Symptoms of low blood cell counts (low red blood cells, low white blood cells, and low platelets) are common during treatment with Niraparib . They can be a sign of serious bone marrow problems, including MDS or AML. These symptoms may include the following:WeaknessFeeling tiredWeight lossFrequent infectionsFeverShortness of breathBlood in urine or stoolBruising or bleeding more easilyYour doctor will do blood tests to check your blood cell counts before treatment with Niraparib . You will be tested weekly for the first month of treatment with Niraparib , monthly for the next 11 months of treatment, and from time to time afterward.High blood pressure is common during treatment with Niraparib , and it can become serious. Your doctor will check your blood pressure and heart rate at least weekly for the first two months, then monthly for the first year, and as needed thereafter during your treatment with Niraparib .Posterior reversible encephalopathy syndrome (PRES) is a condition that affects the brain and may happen during treatment with Niraparib . If you have headache, vision changes, confusion, or seizure, with or without high blood pressure, please contact your doctor.Before starting to take Niraparib , tell your doctor about all of your medical conditions, including if you:Have heart problemsHave liver problemsHave high blood pressureAre allergic to FD&C Yellow No. 5 (tartrazine) or aspirin. Niraparib capsules contain tartrazine, which may cause allergic-type reactions (including bronchial asthma) in certain people, especially people who also have an allergy to aspirinAre pregnant or plan to become pregnant. Niraparib may harm an unborn baby and may cause loss of pregnancy (miscarriage)If you are able to become pregnant, you should use effective birth control (contraception) during treatment with Niraparib and for 6 months after taking the last dose of Niraparib If you are able to become pregnant, your doctor may perform a pregnancy test before you start treatment with Niraparib You should tell your doctor right away if you become pregnantAre breastfeeding or plan to breastfeedNiraparib may harm your baby.