Mekinist Trametinib 2 mg Tablets (Copy)

Description

Mekinist (Trametinib 2mg) is a prescription medicine used: alone or in combination with a medicine called dabrafenib to treat a type of skin cancer called melanoma: that has spread to other parts of the body or cannot be removed by surgery, and that has a certain type of abnormal “BRAF” gene. in combination with dabrafenib, to help prevent melanoma that has a certain type of abnormal “BRAF” gene from coming back after the cancer has been removed by surgery. Mekinist should not be used to treat people who already have received a BRAF inhibitor for treatment of their melanoma, and it did not work or is no longer working. in combination with dabrafenib to treat a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to other parts of the body, and that has a certain type of abnormal “BRAF” gene. in combination with dabrafenib to treat a type of thyroid cancer called anaplastic thyroid cancer (ATC) that has spread to other parts of the body and you have no satisfactory treatment options, and that has a certain type of abnormal “BRAF” gene What are the possible side effects of Mekinist? Mekinist may cause serious side effects, including: See “What is the most important information I should know about Mekinist?” bleeding problems. Mekinist can cause serious bleeding problems, especially in your brain or stomach, that can lead to death. Call your healthcare provider and get medical help right away if you have any signs of bleeding, including: headaches, dizziness, or feeling weak cough up blood or blood clots vomit blood or your vomit looks like “coffee grounds” red or black stools that look like tar inflammation of the intestines, or tears (perforation) of the stomach or intestines. Mekinist can cause inflammation of your intestines, or tears in the stomach or intestines that can lead to death. Tell your healthcare provider immediately if you have any of the following symptoms: bleeding. see “bleeding problems” above diarrhea (loose stools) or more bowel movements than usual stomach-area (abdomen) pain or tenderness fever nausea blood clots. Mekinist can cause blood clots in your arms or legs, which can travel to your lungs and can lead to death. Get medical help right away if you have the following symptoms: chest pain sudden shortness of breath or trouble breathing pain in your legs with or without swelling swelling in your arms or legs a cool pale arm or leg heart problems, including heart failure. Your healthcare provider should check your heart function before and during treatment with Mekinist. Call your healthcare provider right away if you have any of the following signs and symptoms of a heart problem: feeling like your heart is pounding or racing shortness of breath swelling of your ankles and feet feeling lightheaded eye problems. Mekinist can cause severe eye problems that might lead to blindness. Call your healthcare provider right away if you get these symptoms of eye problems: blurred vision, loss of vision, or other vision changes see color dots halo (seeing blurred outline around objects) eye pain, swelling, or redness lung or breathing problems. Mekinist can cause lung or breathing problems. Tell your healthcare provider if you have any new or worsening symptoms of lung or breathing problems, including: shortness of breath cough fever. Fever is common during treatment with Mekinist and dabrafenib, but it may also be serious. When taking Mekinist with dabrafenib, fever may happen more often or may be more severe. In some cases, chills or shaking chills, too much fluid loss (dehydration), low blood pressure, dizziness, or kidney problems may happen with the fever. Call your healthcare provider right away if you get a fever during treatment with Mekinist.